021-51111890
购物车（）
sales@molnova.cn
IU-1
CAS No. 314245-33-5
IU-1 ( USP14 inhibitor IU1 )
产品货号. M14014 CAS No. 314245-33-5
IU-1 (USP14 inhibitor IU1) is a specific, small molecule inhibitor of deubiquitinating enzyme USP14 with IC50 of 4-5 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥437 | 有现货 |
|
| 10MG | ￥616 | 有现货 |
|
| 25MG | ￥1183 | 有现货 |
|
| 50MG | ￥2041 | 有现货 |
|
| 100MG | ￥3629 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称IU-1
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述IU-1 (USP14 inhibitor IU1) is a specific, small molecule inhibitor of deubiquitinating enzyme USP14 with IC50 of 4-5 uM.
-
产品描述IU-1 (USP14 inhibitor IU1) is a specific, small molecule inhibitor of deubiquitinating enzyme USP14 with IC50 of 4-5 uM; displays no activity against other human eight DUBs (Uch37, Uch-L1/L3, USP7, etc.); enhances proteasomal degradation in vivo, attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice; also inhibits Dengue virus replication.
-
同义词USP14 inhibitor IU1
-
通路Proteasome/Ubiquitin
-
靶点DUB
-
受体USP14
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number314245-33-5
-
分子量300.38
-
分子式C18H21FN2O
-
纯度>98% (HPLC)
-
溶解度DMSO: 30 mg/mL (100 mM); Ethanol: 15 mg/mL (50 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESCC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3
-
化学全称1-[1-(4-fluorophenyl)-2,5-dimethylpyrrol-3-yl]-2-pyrrolidin-1-ylethanone
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
2. Nag DK, et al. Virus Res. 2012 Apr;165(1):103-6.
3. Lahaie N, et al. J Biol Chem. 2016 Mar 25;291(13):7156-70.
4. Min JW, et al. J Neurochem. 2017 Mar;140(5):826-833.
产品手册
关联产品
-
PR-619
PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM in a cell-free assay.
-
NSC112200
NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2.
-
MK8745
MK-8745 is a potent and selective Aurora A inhibitor.
