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IMR-1A
CAS No. 331862-41-0
IMR-1A ( IMR-1A; IMR 1A; Inhibitor of Mastermind Recruitment-1 Acid )
产品货号. M17483 CAS No. 331862-41-0
IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2001 | 有现货 |
|
| 10MG | ￥2989 | 有现货 |
|
| 25MG | ￥5038 | 有现货 |
|
| 50MG | ￥7169 | 有现货 |
|
| 100MG | ￥9639 | 有现货 |
|
| 500MG | ￥19683 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称IMR-1A
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
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产品描述IMR-1A is a metabolite of IMR-1. IMR-1A acts as Notch inhibitor and targeting gene transcription by disrupting Mam1 recruitment to chromatin.
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同义词IMR-1A; IMR 1A; Inhibitor of Mastermind Recruitment-1 Acid
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通路Others
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靶点Other Targets
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受体Notch
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研究领域Cancer
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适应症——
化学信息
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CAS Number331862-41-0
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分子量325.36
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分子式C13H11NO5S2
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纯度98%
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溶解度DMSO : ≥ 31 mg/mL; 95.28 mM
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SMILESO=C(O)COc1ccc(/C=C/2\SC(=S)NC2=O)cc1OC
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化学全称2-[2-Methoxy-4-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Astudillo L,et al. The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Cancer Res. 2016 Jun 15;76(12):3593-603.
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