Hydroxy-PP-Me ( —— )

产品货号. M37254 CAS No. 833481-77-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Hydroxy-PP-Me
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Hydroxy-PP-Me 是一种有效的特异性 CBR1 抑制剂，其 IC50 为 759 nM。Hydroxy-PP-Me 抑制血清戒断诱导的细胞凋亡 (apoptosis)。与单独使用 As2O3 相比，Hydroxy-PP-Me 增加了 As2O3 诱导的凋亡细胞死亡
产品描述

Hydroxy-PP-Me is a potent and specific CBR1 inhibitor with an IC50 of 759 nM. Hydroxy-PP-Me inhibits serum-withdrawal-induced apoptosis. Hydroxy-PP-Me increases As2O3-induced apoptotic cell death compared with As2O3 alone.
体外实验

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体内实验

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同义词

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通路

Apoptosis
靶点

Apoptosis
受体

Apoptosis
研究领域

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适应症

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1. Tanaka M, et al. An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol. 2005 May;3(5):e128.?

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