Haloperidol ( McN-JR 1625; NSC 170973; NSC 615296; R 1625 )

产品货号. M14873 CAS No. 52-86-8

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Haloperidol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Haloperidol has been found to be highlt potent neuroleptic by relieving nervous through the depression of nerve function.
产品描述

Haloperidol has been found to be highlt potent neuroleptic by relieving nervous through the depression of nerve function. Besides, Haloperidol has shown about 50-fold potency than chiorpromazine, the other antipsychotic drug. Haloperidol has shown beneficial effects in the treatment of delusions and hallucinations. These effects are mainly achieved through blockage of dopamine receptors in the mesocortex and limbic system.
同义词

McN-JR 1625; NSC 170973; NSC 615296; R 1625
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT; Dopamine
研究领域

Neurological Disease
适应症

——

CAS Number

52-86-8
分子量

375.87
分子式

C21H23ClFNO2
纯度

>98%(HPLC)
溶解度

Ethanol: 8 mg/mL (21.28 mM); DMSO: 75 mg/mL (199.54 mM)
SMILES

C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
化学全称

4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

1.Cai G, et al. Mol Pharmacol. 1999 Nov;56(5):989-96.

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