H-Ile-Pro-Pro-OH

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM.

H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. (In Vitro):Vitro: Ile-Pro-Pro (IPP) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs).(In Vivo):Vivo: Ile-Pro-Pro attenuates arterial dysfunction in L-NAME-treated rats Ile-Pro-Pro (IPP) decreases blood pressure in spontaneously hypertensive rats (SHR) . Ile-Pro-Pro (IPP) attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice.

Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs).

Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated rats.Ile-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) .Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient(apoE(-/-)) mice.

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Metabolic Enzyme/Protease

ACE

IC50: 5 μM (ACE)

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26001-32-1

325.4

C16H27N3O4

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years