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GUT-70
CAS No. 161633-75-6
GUT-70 ( GUT70 )
产品货号. M12357 CAS No. 161633-75-6
GUT-70 is a tricyclic coumarin derived from Calophyllum brasiliense, markedly reduces cell proliferation.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GUT-70
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GUT-70 is a tricyclic coumarin derived from Calophyllum brasiliense, markedly reduces cell proliferation.
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产品描述GUT-70 is a tricyclic coumarin derived from Calophyllum brasiliense, markedly reduces cell proliferation, viability through G1 cell cycle arrest and increases apoptosis; shows binding affinity to heat-shock protein 90 (Hsp90) and ubiquitin-dependent proteasomal degradation of Hsp90 client proteins, including cyclin D1, Raf-1, Akt, and mt-p53; also inhibits HIV-1 replication in both acutely and chronically infected cells through suppression of NF-κB.
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同义词GUT70
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通路Apoptosis
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靶点Apoptosis
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受体Apoptosis
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研究领域——
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适应症——
化学信息
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CAS Number161633-75-6
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分子量382.46
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分子式C23H26O5
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称2H,8H-Benzo[1,2-b:3,4-b']dipyran-8-one, 5-methoxy-2,2-dimethyl-6-(2-methyl-1-oxo-2-butenyl)-10-propyl-, (E)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Kimura S, et al. Int J Cancer. 2005 Jan 1;113(1):158-65.
2. Jin L, et al. Br J Cancer. 2011 Jan 4;104(1):91-100.
3. Kudo E, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):606-9.
2. Jin L, et al. Br J Cancer. 2011 Jan 4;104(1):91-100.
3. Kudo E, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):606-9.
产品手册
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