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GSK2256294A
CAS No. 1142090-23-0
GSK2256294A ( GSK 2256294 )
产品货号. M26704 CAS No. 1142090-23-0
GSK2256294A is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1758 | 有现货 |
|
| 10MG | ￥2811 | 有现货 |
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| 25MG | ￥4674 | 有现货 |
|
| 50MG | ￥6691 | 有现货 |
|
| 100MG | ￥9153 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GSK2256294A
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GSK2256294A is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.
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产品描述GSK2256294A is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.(In Vitro):GSK2256294A displays potent cellular inhibition of sEH with an IC50 of 0.66 nM in an assay developed using a cell line transfected with the human sEH enzyme.(In Vivo):Mice receiving 10 days of cigarette smoke exposure concomitant with oral administration of GSK2256294A exhibits significant, dose-dependent reductions in pulmonary leukocytes and keratinocyte chemoattractant levels. Mice receiving oral administration of GSK2256294A following 10 days of cigarette smoke exposure exhibited significant reductions in pulmonary leukocytes compared to vehicle-treated mice.
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同义词GSK 2256294
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通路Others
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靶点Other Targets
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受体Bacterial; Human Endogenous Metabolite
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研究领域——
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适应症——
化学信息
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CAS Number1142090-23-0
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分子量447.5
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分子式C21H24F3N7O
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纯度>98% (HPLC)
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溶解度——
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SMILESCNc1nc(C)nc(N[C@H]2CCC[C@H](C2)C(=O)NCc2ccc(cc2C(F)(F)F)C#N)n1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Takagi H, et al. Morphine-like analgesia by a new dipeptide, L-tyrosyl-L-arginine (Kyotorphin) and its analogue. Eur J Pharmacol. 1979;55(1):109-111.
产品手册
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