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D3-βArr
CAS No. 662164-09-2
D3-βArr ( NCGC00379308 )
产品货号. M20139 CAS No. 662164-09-2
D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR) which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥446 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
|
| 25MG | ￥1588 | 有现货 |
|
| 50MG | ￥2957 | 有现货 |
|
| 100MG | ￥4512 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称D3-βArr
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR) which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
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产品描述D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR) which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
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同义词NCGC00379308
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通路Others
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靶点Other Targets
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受体thyrotropin receptor (TSHR)
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研究领域——
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适应症——
化学信息
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CAS Number662164-09-2
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分子量333.43
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分子式C20H23N5
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纯度>98% (HPLC)
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溶解度DMSO: 100 mg/mL (299.91 mM)
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SMILESCC(Nc1nc(nc2ccccc12)N1CCNCC1)c1ccccc1
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化学全称N-(1-Phenylethyl)-2-(1-piperazinyl)-4-quinazolinamine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Neumann S et al. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro. J Pharmacol Exp Ther. 2018 Jan;364(1):38-45.
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