• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

GSK-25

CAS No. 874119-56-9

GSK-25 ( —— )

产品货号. M17637 CAS No. 874119-56-9

GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥437 有现货
5MG ¥680 有现货
10MG ¥964 有现货
25MG ¥1458 有现货
50MG ¥2317 有现货
100MG ¥3872 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    GSK-25
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
  • 产品描述
    GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    RSK1; mTOR (p70S6K)
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    874119-56-9
  • 分子量
    513.34
  • 分子式
    C24H16Cl2F2N6O
  • 纯度
    98%
  • 溶解度
    ——
  • SMILES
    Clc1nccc(c1)C=2NC(C)=C(C(N=2)c3ccc(Cl)cc3F)C(=O)Nc4cc5cnnc5cc4F
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Sehon CA, et al. J Med Chem. 2008 Nov 13;51(21):6631-4.
产品手册
关联产品
  • CNS-5161 hydrochlori...

    CNS-5161 hydrochloride is a new antagonist of NMDA ion-channel. It interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.

  • 1-(3,4-dimethoxyphen...

    1-(3,4-Dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol shows anti-staphylococcal activity against a total of five multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus strains and the minimum inhibitory concentrations (MICs) are in the range of 128-256 ug/ml.

  • Mequitazine

    Mequitazine is an effective, nonsedative and long-acting histamine H1 antagonist.