Emixustat ( ACU-4429 )

产品货号. M10502 CAS No. 1141777-14-1

Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
50MG	￥8068	有现货
100MG	￥14094	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

Emixustat
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.
产品描述

Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM; reduces the production of visual chromophore (11-cis retinal) in wild-type mice following a single oral dose (ED50 = 0.18 mg/kg).Other Indication Phase 3 Clinical
同义词

ACU-4429
通路

Others
靶点

Other Targets
受体

Other Targets
研究领域

Other Indications
适应症

Other Disease

化学信息

CAS Number

1141777-14-1
分子量

263.38
分子式

C16H25NO2
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 43 mg/mL
SMILES

C1CCC(CC1)COC2=CC=CC(=C2)C(CCN)O
化学全称

Benzenemethanol, α-(2-aminoethyl)-3-(cyclohexylmethoxy)-, (αR)-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Kiser PD, et al. Nat Chem Biol. 2015 Jun;11(6):409-15.
2. Bavik C, et al. PLoS One. 2015 May 13;10(5):e0124940.
3. Zhang J, et al. J Clin Invest. 2015 Jul 1;125(7):2781-94.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

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