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Emixustat
CAS No. 1141777-14-1
Emixustat ( ACU-4429 )
产品货号. M10502 CAS No. 1141777-14-1
Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥8068 | 有现货 |
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| 100MG | ￥14094 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Emixustat
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.
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产品描述Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM; reduces the production of visual chromophore (11-cis retinal) in wild-type mice following a single oral dose (ED50 = 0.18 mg/kg).Other Indication Phase 3 Clinical
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同义词ACU-4429
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number1141777-14-1
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分子量263.38
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分子式C16H25NO2
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 43 mg/mL
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SMILESC1CCC(CC1)COC2=CC=CC(=C2)C(CCN)O
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化学全称Benzenemethanol, α-(2-aminoethyl)-3-(cyclohexylmethoxy)-, (αR)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Kiser PD, et al. Nat Chem Biol. 2015 Jun;11(6):409-15.
2. Bavik C, et al. PLoS One. 2015 May 13;10(5):e0124940.
3. Zhang J, et al. J Clin Invest. 2015 Jul 1;125(7):2781-94.
2. Bavik C, et al. PLoS One. 2015 May 13;10(5):e0124940.
3. Zhang J, et al. J Clin Invest. 2015 Jul 1;125(7):2781-94.
产品手册
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