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GS-9451
CAS No. 1310824-24-8
GS-9451 ( GS9451;Vedroprevir )
产品货号. M11250 CAS No. 1310824-24-8
GS-9451 (Vedroprevir) is a potent HCV NS3/4A protease inhibitor with Ki of 0.41 nM, inhibits HCV GT-1b NS3/4A with IC50 of 3.2 nM in enzymatic assays.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GS-9451
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GS-9451 (Vedroprevir) is a potent HCV NS3/4A protease inhibitor with Ki of 0.41 nM, inhibits HCV GT-1b NS3/4A with IC50 of 3.2 nM in enzymatic assays.
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产品描述GS-9451 (Vedroprevir) is a potent HCV NS3/4A protease inhibitor with Ki of 0.41 nM, inhibits HCV GT-1b NS3/4A with IC50 of 3.2 nM in enzymatic assays; exhibits low toxicity and high selectivity over mammalian proteases.HCV Infection Phase 2 Discontinued
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同义词GS9451;Vedroprevir
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通路Microbiology/Virology
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靶点HCV
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受体HCV
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研究领域Infection
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适应症HCV Infection
化学信息
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CAS Number1310824-24-8
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分子量910.53
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分子式C45H60ClN7O9S
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纯度>98% (HPLC)
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溶解度——
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SMILESCCC1CC1(C(=O)O)NC(=O)C2CC(CN2C(=O)C(C(C)(C)C)NC(=O)OC3CC4CC4C3)OC5=CC(=NC6=C5C=CC(=C6Cl)OCCN7CCOCC7)C8=CSC(=N8)NC(C)C
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化学全称(1R,2R)-1-((2S)-1-((S)-2-(((((1R,3r,5S)-bicyclo[3.1.0]hexan-3-yl)oxy)carbonyl)amino)-3,3-dimethylbutanoyl)-4-((8-chloro-2-(2-(isopropylamino)thiazol-4-yl)-7-(2-morpholinoethoxy)quinolin-4-yl)oxy)pyrrolidine-2-carboxamido)-2-ethylcyclopropane-1-carboxylic
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Sheng XC, et al. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2629-34.
2. Dvory-Sobol H, et al. Antimicrob Agents Chemother. 2012 Oct;56(10):5289-95.
3. Yang H, et al. Antimicrob Agents Chemother. 2014;58(2):647-53.
2. Dvory-Sobol H, et al. Antimicrob Agents Chemother. 2012 Oct;56(10):5289-95.
3. Yang H, et al. Antimicrob Agents Chemother. 2014;58(2):647-53.
产品手册
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