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GLX351322
CAS No. 835598-94-2
GLX351322 ( —— )
产品货号. M21200 CAS No. 835598-94-2
GLX351322 是 NADPH 氧化酶 4 抑制剂，IC50 为 5 μM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥340 | 有现货 |
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| 5MG | ￥551 | 有现货 |
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| 10MG | ￥907 | 有现货 |
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| 25MG | ￥2066 | 有现货 |
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| 50MG | ￥3532 | 有现货 |
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| 100MG | ￥5241 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GLX351322
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GLX351322 是 NADPH 氧化酶 4 抑制剂，IC50 为 5 μM。
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产品描述GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
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体外实验GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells (IC50, 40 μM).
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体内实验GLX351322 (3.8 mg/kg/day, p.o.) ameliorates HFD-induced hyperglycemia in mice.
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同义词——
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通路Membrane Transporter/Ion Channel
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靶点NADPH
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受体NOX4
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研究领域——
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适应症——
化学信息
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CAS Number835598-94-2
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分子量431.5
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分子式C21H25N3O5S
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纯度>98% (HPLC)
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溶解度DMSO:20 mg/mL (46.35 mM; Need ultrasonic)
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SMILESCCOC(=O)c1c(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)sc2c1CCC2
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化学全称Ethyl 2-[[2-[4-(furan-2-carbonyl)piperazin-1-yl]acetyl]amino]-56-dihydro-4H-cyclopenta-[b]thiophene-3-carboxylate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Anvari Ebrahim Wikstr?m Per Walum Eriket al. The novel NADPH oxidase 4 inhibitor GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice[J]. Free Radical Research 49(11):1-32.
