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G907
CAS No. ——
G907 ( G-907;G 907 )
产品货号. M17102 CAS No. ——
G907 is a potent, selective small-molecule antagonist of ATP-binding cassette (ABC) transporter MsbA with IC50 of 18 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称G907
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述G907 is a potent, selective small-molecule antagonist of ATP-binding cassette (ABC) transporter MsbA with IC50 of 18 nM.
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产品描述G907 is a potent, selective small-molecule antagonist of ATP-binding cassette (ABC) transporter MsbA with IC50 of 18 nM; traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket, inhibits the growth of wild-type E. coli and Klebsiella pneumoniae with MIC of 5.6 ug/ml.
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同义词G-907;G 907
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量433.93
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分子式C26H24ClNO3
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(O)/C=C/C1=C(C2CC2)C3=CC(OC(C4=C(C5CC5)C=CC=C4Cl)C)=CC=C3N=C1
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化学全称(E)-3-(6-(1-(2-chloro-6-cyclopropylphenyl)ethoxy)-4-cyclopropylquinolin-3-yl)acrylic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Ho H, et al. Nature. 2018 May 2. doi: 10.1038/s41586-018-0083-5.
产品手册
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