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G0507

CAS No. 1223998-29-5

G0507 ( G0507 )

产品货号. M10857 CAS No. 1223998-29-5

G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥4026 有现货
50MG ¥13365 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    G0507
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity.
  • 产品描述
    G 0507 is a novel inhibitor of the bacterial LolCDE ABC transporter, binds to LolCDE and stimulates its ATPase activity; results in accumulation of fully processed Lpp, an outer membrane lipoprotein, in the inner membrane in E. coli cells, still binds to LolCDE harboring a LolCQ258K mutation, which confers high-level resistance to G0507 in vivo, but no longer stimulates ATPase activity; a useful chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria.
  • 同义词
    G0507
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1223998-29-5
  • 分子量
    353.40
  • 分子式
    C18H15N3O3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    5-(4-methoxyphenyl)-6-(5-methylthiophen-2-yl)-1,7-dihydro-2H-pyrrolo[2,3-d]pyrimidine-2,4(3H)-dione

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Nickerson NN, et al. Antimicrob Agents Chemother. 2018 Jan 16. pii: AAC.02151-17.
产品手册
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