Fostemsavir ( BMS-663068; BMS 663068; Fostemsavir )

产品货号. M19191 CAS No. 864953-29-7

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Datasheet

HNMR

HPLC

MSDS

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产品名称

Fostemsavir
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
产品描述

Fostemsavir, also known as BMS-663068, is a oral, safe and effective HIV-1 attachment inhibitor. BMS-663068 is a prodrug of the small-molecule inhibitor BMS-626529, which inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.
同义词

BMS-663068; BMS 663068; Fostemsavir
通路

Angiogenesis
靶点

Adrenergic Receptor
受体

HIV-1
研究领域

Infection
适应症

——

CAS Number

864953-29-7
分子量

583.5
分子式

C25H26N7O8P
纯度

98%
溶解度

DMSO : ≥ 100 mg/mL 171.38 mM H2O : 20 mg/mL 34.28 mM;
SMILES

COc1cnc(-n2cnc(C)n2)c2n(COP(O)(O)=O)cc(C(=O)C(=O)N3CCN(CC3)C(=O)c3ccccc3)c12
化学全称

(3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl)methyl dihydrogen phosphate

1. Lalezari JP, et al. Lancet HIV. 2015 Oct;2(10):e427-37.

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