Filaminast ( WAY-PDA-641;PDA-641;WAY-123641 )

产品货号. M11714 CAS No. 141184-34-1

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HPLC

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Handing Instructions

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产品名称

Filaminast
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Filaminast (WAY-PDA-641;PDA-641;WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3.
产品描述

Filaminast (WAY-PDA-641;PDA-641;WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3; significantly potentiates the relaxant effects of albuterol, reverses tracheal contractions induced by prostaglandin F2 alpha, leukotriene D4 or histamine in a biphasic manner.Asthma Phase 2 Discontinued
同义词

WAY-PDA-641;PDA-641;WAY-123641
通路

Angiogenesis
靶点

PDE
受体

PDE
研究领域

Inflammation/Immunology
适应症

Asthma

1. Heaslip RJ, et al. J Pharmacol Exp Ther. 1994 Feb;268(2):888-96.

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