Fidaxomicin ( OPT-80 | PAR-101 )

产品货号. M16356 CAS No. 873857-62-6

Fidaxomicin（OPT-80；PAR-101）是一类新型窄谱大环抗生素化合物。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥284	有现货
10MG	￥324	有现货
25MG	￥437	有现货
50MG	￥599	有现货
100MG	￥1021	有现货
200MG	￥1507	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Fidaxomicin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fidaxomicin（OPT-80；PAR-101）是一类新型窄谱大环抗生素化合物。
产品描述

Fidaxomicin(OPT-80; PAR-101) is a?new class of narrow spectrum macrocyclic antibiotic drug, selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria.Bacterial Infection Approved(In Vitro):Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.Fidaxomicin is not inhibitory to commonly cultured bowel commensals (MIC90 >1024?μg/mL).(In Vivo):Fidaxomicin (0-5 mg/kg, Orally, once a day for 5 days) completely prevents the lethality of the animals and prevents the occurrence of relapses in a hamster model for pseudomembranous colitis.
体外实验

Fidaxomicin selectively eradicates pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.Fidaxomicin is not inhibitory to commonly cultured bowel commensals (MIC90 >1024?μg/mL).
体内实验

Fidaxomicin (0-5 mg/kg, Orally, once a day for 5 days) completely prevents the lethality of the animals and prevents the occurrence of relapses in a hamster model for pseudomembranous colitis. Animal Model:Male Golden Syrian hamsters (80-100 g, Hamster model for pseudomembranous colitis)Dosage:0.2, 1, and 5 mg/kg Administration:Orally, once a day for 5 days, beginning 8 h after infectionResult:Completely prevented the lethality of the animals. Completely prevented the development of antibiotic-induced C. difficile colitis in hamsters at doses as low as 0.2 mg/kg.
同义词

OPT-80 | PAR-101
通路

GPCR/G Protein
靶点

Antibacterial
受体

RNApolymerase
研究领域

Infection
适应症

Bacterial Infection

化学信息

CAS Number

873857-62-6
分子量

1058.039
分子式

C52H74Cl2O18
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 33 mg/mL
SMILES

O=C(O[C@@H]1[C@@H](C)O[C@@H](OC/C2=C\C=C\C[C@H](O)/C(C)=C/[C@H](CC)[C@@H](O[C@H]3[C@@H](O)[C@@H](O)[C@H](OC(C(C)C)=O)C(C)(C)O3)/C(C)=C/C(C)=C/C[C@@H]([C@H](O)C)OC2=O)[C@@H](OC)[C@H]1O)C4=C(O)C(Cl)=C(O)C(Cl)=C4CC
化学全称

Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1