
FCCP
CAS No. 370-86-5
FCCP ( Trifluoromethoxy carbonylcyanide phenylhydrazone )
产品货号. M14275 CAS No. 370-86-5
FCCP 是线粒体氧化磷酸化的有效解偶联剂,可通过跨细胞膜运输质子来破坏 ATP 合成。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥292 | 有现货 |
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10MG | ¥413 | 有现货 |
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25MG | ¥745 | 有现货 |
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50MG | ¥1345 | 有现货 |
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100MG | ¥2511 | 有现货 |
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200MG | ¥4196 | 有现货 |
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500MG | ¥6707 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称FCCP
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述FCCP 是线粒体氧化磷酸化的有效解偶联剂,可通过跨细胞膜运输质子来破坏 ATP 合成。
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产品描述FCCP is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes.(In Vitro):FCCP (5 μM) results in a concentration-dependent decrease in Aβ and APPsβ production in K695sw cells. FCCP inhibits processing of wild-type APP. FCCP does not alter cellular ATP levels at any of the concentrations measured. The effects of FCCP on APP catabolism are independent of secondary effects on oxidative phosphorylation or the result of reduced cell viability in K695sw cells. FCCP (5 μM or 500 nM), baf A1, and NH4Cl induce changes in Tf-Tx and Tf-F cellular fluorescence in K695 cells. FCCP (200 nM) protects and enhances the follicle integrity in cat ovarian tissue during short-term in vitro culture. But FCCP does not appear to exert a beneficial or detrimental effect during ovarian tissue cryopreservation.
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体外实验——
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体内实验——
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同义词Trifluoromethoxy carbonylcyanide phenylhydrazone
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通路Others
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靶点Other Targets
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受体Others
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研究领域Cancer
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适应症——
化学信息
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CAS Number370-86-5
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分子量254.17
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分子式C10H5F3N4O
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纯度>98% (HPLC)
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溶解度Ethanol: 50 mg/mL (196.71 mM) DMSO: 50 mg/mL (196.71 mM) Water: <1 mg/mL
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SMILESN#C/C(C#N)=N/NC1=CC=C(OC(F)(F)F)C=C1
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化学全称N-(4-(trifluoromethoxy)phenyl)carbonohydrazonoyl dicyanide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.HEYTLER PG et al. A new class of uncoupling agents--carbonyl cyanide phenylhydrazones. Biochem Biophys Res Commun. 1962 May 4;7:272-5.
产品手册




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