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F-11440
CAS No. 179756-58-2
F-11440 ( Eptapirone )
产品货号. M12716 CAS No. 179756-58-2
A potent, selective 5-HT1A receptor agonist with Ki of 4.8 nM, pKi of 8.33.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥680 | 有现货 |
|
| 10MG | ￥1158 | 有现货 |
|
| 25MG | ￥2292 | 有现货 |
|
| 50MG | ￥4261 | 有现货 |
|
| 100MG | ￥6059 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称F-11440
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent, selective 5-HT1A receptor agonist with Ki of 4.8 nM, pKi of 8.33.
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产品描述A potent, selective 5-HT1A receptor agonist with Ki of 4.8 nM, pKi of 8.33; shows ≥shows 100-fold higher affinity for the other serotonin receptor subtypes, and has no detectable antidopaminergic activity and antihistaminergic activity; decreases the forskolin-induced increase in AMP in HeLa cells expressing human 5-HT1A receptors; produces anxiolytic- and antidepressant-like effects in animal models.Anxiety Phase 1 Discontinued
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同义词Eptapirone
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT1A
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研究领域Neurological Disease
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适应症Anxiety
化学信息
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CAS Number179756-58-2
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分子量345.40
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分子式C16H23N7O2
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纯度>98% (HPLC)
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溶解度DMSO: 6 mg/mL (Need ultrasonic)
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SMILESO=C(N1C)N(CCCCN2CCN(C3=NC=CC=N3)CC2)N=CC1=O
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化学全称1,2,4-Triazine-3,5(2H,4H)-dione, 4-methyl-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Koek W, et al. J Pharmacol Exp Ther. 1998 Oct;287(1):266-83.
2. Prinssen EP, et al. Eur J Pharmacol. 2002 Oct 25;453(2-3):217-21.
3. Pauwels PJ, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14.
2. Prinssen EP, et al. Eur J Pharmacol. 2002 Oct 25;453(2-3):217-21.
3. Pauwels PJ, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14.
产品手册
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