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F-1

CAS No. 2244775-31-1

F-1 ( —— )

产品货号. M26211 CAS No. 2244775-31-1

?F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.?F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1936 有现货
10MG ¥2811 有现货
25MG ¥4496 有现货
50MG ¥6342 有现货
100MG ¥8829 有现货
500MG ¥18063 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    F-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ?F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.?F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.
  • 产品描述
    ?F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.?F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.
  • 同义词
    ——
  • 通路
    Immunology/Inflammation
  • 靶点
    ROS
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2244775-31-1
  • 分子量
    519.0
  • 分子式
    C22H27ClN8O3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    COc1nc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Hamilton JA, Bhamidipati SP, Kodali DR, Small DM. The interfacial conformation and transbilayer movement of diacylglycerols in phospholipid bilayers. J Biol Chem. 1991 Jan 15;266(2):1177-86.
产品手册
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