
Etofibrate
CAS No. 31637-97-5
Etofibrate ( Nicotinic Acid )
产品货号. M14031 CAS No. 31637-97-5
依托贝特是氯贝特和烟酸的组合,用于治疗高脂血症。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥324 | 有现货 |
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25MG | ¥527 | 有现货 |
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50MG | ¥689 | 有现货 |
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100MG | ¥1053 | 有现货 |
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200MG | ¥1604 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Etofibrate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述依托贝特是氯贝特和烟酸的组合,用于治疗高脂血症。
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产品描述Etofibrate is a combination of clofibrate and niacin, used to treat hyperlipemia.(In Vivo):Etofibrate is the ethandiol-1,2 diester of the nicotinic and clofibric acids. Etofibrate has been shown to be a potent hypolipidemic agent in animal and human. After 10 days of treatment with Etofibrate, the rats show a body weight similar to that found in the control animals but their liver weight is significantly enhanced whereas plasma cholesterol and triacylglycerol levels are decreased. Etofibrate treatment increases the bile flow of the animals, the effect being especially manifest during the first 2 hr after interruption of the enterohepatic circulation and the difference with the controls becomes statistically significant at 30 and 90 min. The cumulative amount of bile secreted plotted against time shows a highly significant linear correlation for both control and Etofibrate treated rats, the slope being significantly higher for the Etofibrate group than for controls.
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体外实验——
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体内实验Etofibrate is the ethandiol-1,2 diester of the nicotinic and clofibric acids. Etofibrate has been shown to be a potent hypolipidemic agent in animal and human. After 10 days of treatment with Etofibrate, the rats show a body weight similar to that found in the control animals but their liver weight is significantly enhanced whereas plasma cholesterol and triacylglycerol levels are decreased. Etofibrate treatment increases the bile flow of the animals, the effect being especially manifest during the first 2 hr after interruption of the enterohepatic circulation and the difference with the controls becomes statistically significant at 30 and 90 min. The cumulative amount of bile secreted plotted against time shows a highly significant linear correlation for both control and Etofibrate treated rats, the slope being significantly higher for the Etofibrate group than for controls.
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同义词Nicotinic Acid
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通路Others
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靶点Other Targets
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受体Others
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研究领域Other Indications
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适应症——
化学信息
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CAS Number31637-97-5
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分子量363.79
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分子式C18H18ClNO5
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纯度>98% (HPLC)
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溶解度Ethanol: 73 mg/mL (200.66 mM); DMSO: 73 mg/mL (200.66 mM)
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SMILESO=C(C1=CC=CN=C1)OCCOC(C(C)(OC2=CC=C(Cl)C=C2)C)=O
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化学全称2-[2-(4-Chlorophenoxy)-2-methylpropanoyl]oxyethyl pyridine-3-carboxylate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Herrera E, et al. Biochim Biophys Acta, 1988, 963(1), 42-52.
产品手册




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