Espindolol ( AGI-001; MT-102; AGI001; MT102; AGI 001; MT 102 )

产品货号. M27876 CAS No. 26328-11-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

Espindolol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Espindolol is a novel non-selective β blocker with central 5-HT1a and partial β2 receptor agonist effects.
产品描述

Espindolol is a novel non-selective β blocker with central 5-HT1a and partial β2 receptor agonist effects.(In Vivo):Placebo-treated rats progressively lost body weight (-15.5 ± 7.2 g), lean mass (-1.5 ± 4.2 g), and fat mass (-15.6 ± 2.7 g), while espindolol treatment increased body weight (+8.0 ± 6.1 g, p < 0.05), particularly lean mass (+43.4 ± 3.5 g, p < 0.001), and reduced fat mass further (-38.6 ± 3.4 g, p < 0.001). Anabolic/catabolic signaling was assessed in gastrocnemius muscle. Espindolol decreased proteasome and caspase-3 proteolytic activities by approximately 50 % (all p < 0.05).
同义词

AGI-001; MT-102; AGI001; MT102; AGI 001; MT 102
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

——
研究领域

——
适应症

——

1.Fujimoto Y, et al. Fixed drug eruption due to allylisopropylacetylurea. Contact Dermatitis. 1993 May;28(5):282-4.

计算器

产品手册

关联产品

Niaprazine

Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.
(S)-Amlodipine Besyl...

Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication.
Loxapine succinate

A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.