ELOVL1-IN-1
CAS No. 2227482-41-7
ELOVL1-IN-1 ( 1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide )
产品货号. M28774 CAS No. 2227482-41-7
ELOVL1-IN-1 is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥3345 | 有现货 |
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10MG | ¥5006 | 有现货 |
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25MG | ¥7979 | 有现货 |
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50MG | ¥10773 | 有现货 |
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100MG | ¥14499 | 有现货 |
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500MG | ¥29079 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称ELOVL1-IN-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述ELOVL1-IN-1 is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD).
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产品描述ELOVL1-IN-1 is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD).(In Vitro):Administration of 1 nM-10 μM ELOVL1-IN-1 for 48 h reduces the level of VLCFA, lysophosphatidylcholine (LPC) in adrenoleukodystrophy (ALD) patient fibroblasts and healthy human fibroblasts, ALD patient B‐lymphocytes, and human microglia.(In Vivo):Oral dministration of ELOVL1-IN-1 reduces of a VLCFA level, specifically C26:0 LPC level in blood of ABCD1 knockout mice (0.5-64 mg/kg; 28 days), wild‐type (WT) rats (30-300 mg/kg; 7 days), and cynomolgous monkeys (30 mg/kg; 7 days).
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同义词1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide
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通路Others
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靶点Other Targets
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受体AhR
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研究领域——
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适应症——
化学信息
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CAS Number2227482-41-7
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分子量340.3
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分子式C18H14F2N4O
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(C1(CC1)c(cccc1)c1F)Nc(cc1)nn1-c1cc(F)ncc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Current Patent Assignee: MAGENTA THERAPEUTICS INC - WO2020/51207, 2020, A2
产品手册
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