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DMXAA

CAS No. 117570-53-3

DMXAA ( ASA-404;Vadimezan )

产品货号. M10596 CAS No. 117570-53-3

A vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM; activates STING dependent innate immune pathways.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥389 有现货
5MG ¥656 有现货
10MG ¥891 有现货
25MG ¥1936 有现货
50MG ¥3499 有现货
100MG ¥3848 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    DMXAA
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM; activates STING dependent innate immune pathways.
  • 产品描述
    A vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM; activates STING dependent innate immune pathways.
  • 同义词
    ASA-404;Vadimezan
  • 通路
    Autophagy
  • 靶点
    Autophagy
  • 受体
    DT-diaphorase
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    117570-53-3
  • 分子量
    282.29
  • 分子式
    C17H14O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 6.5 mg/mL
  • SMILES
    O=C(O)CC1=CC=CC(C2=O)=C1OC3=C2C=CC(C)=C3C
  • 化学全称
    9H-Xanthene-4-acetic acid, 5,6-dimethyl-9-oxo-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Phillips RM. Biochem Pharmacol. 1999 Jul 15;58(2):303-10.
2. Prantner D, et al. J Biol Chem. 2012 Nov 16;287(47):39776-88.
3. Shirey KA, et al. J Leukoc Biol. 2011 Mar;89(3):351-7.
产品手册
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