DMG-PEG2000 ( —— )

产品货号. M23706 CAS No. 160743-62-4

DMG-PEG2000 是一种脂质赋形剂，已与其他脂质组合用于形成脂质纳米颗粒。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
25MG	￥348	有现货
50MG	￥502	有现货
100MG	￥753	有现货
200MG	￥1175	有现货
500MG	￥2341	有现货
1G	获取报价	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

DMG-PEG2000
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

DMG-PEG2000 是一种脂质赋形剂，已与其他脂质组合用于形成脂质纳米颗粒。
产品描述

DMG-PEG2000 is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles. Formulations containing DMG-PEG2000 have been used in the development of lipid nanoparticles for the delivery of mRNA-based vaccines.
体外实验

NP-3 (0.05-1.6 mg/mL; 24 hours) does not decrease the cytotoxicity of cells in 293T, HepG2, A549, and HeLa cell lines, but the DPPC and DMG-PEG coated nanoparticles reduce cell cytotoxicity. In addition, the transfection efficiency of DPPC/DMG-PEG/(lPEI/DNA) nanoparticles (NP-3) in 293 cells is improved, and the maximum transfection efficiency (~76% eGFP positive cells) is observed.
体内实验

NP-3 (oral administration; 150 μg DNA per mouse; single dose) at 12, 24, and 36 h postadministration, luciferin substrate is intraperitoneally injected to verify its permeability. NP-3 group maintains high luciferase expression in the liver, lung, and intestine areas 12-24 h post-treatment.Additionally, NP-3 exhibits 1.5 times higher signal intensity than that of NP-1 or NP-2 group from 12 to 24 h postoral administration.
同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

——
适应症

——

化学信息

CAS Number

160743-62-4
分子量

570.9
分子式

C34H66O6
纯度

>98% (HPLC)
溶解度

DMSO:100 mg/mL (Need ultrasonic)
SMILES

——
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Tianqi Nie, et al. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1.ACS Appl Mater Interfaces. 2019 Aug 21;11(33):29593-29603.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册