Closantel ( NSC 335306 )

产品货号. M15114 CAS No. 57808-65-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Closantel
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases.
产品描述

A veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases; also shows to be an allosteric inhibitor of SPAK and OSR1.Parasite Infection Approved
同义词

NSC 335306
通路

Microbiology/Virology
靶点

Parasite
受体

Antiparasitic
研究领域

Infection
适应症

Parasite Infection

CAS Number

57808-65-8
分子量

663.07
分子式

C22H14Cl2I2N2O2
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 49 mg/mL
SMILES

CC1=CC(C(C#N)C2=CC=C(Cl)C=C2)=C(Cl)C=C1NC(=O)C1=CC(I)=CC(I)=C1O
化学全称

Benzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-

1. AlAmri MA, et al. ChemMedChem. 2017 May 9;12(9):639-645.
2. Gloeckner C, et al. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3424-9.

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