
Cirsimaritin
CAS No. 6601-62-3
Cirsimaritin ( —— )
产品货号. M29601 CAS No. 6601-62-3
Cirsimaritin 具有抗菌、抗炎、抗肿瘤、抗氧化和肾脏保护作用。 Cirsimaritin 与 GABAA 受体上的苯二氮卓位点结合较弱。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1701 | 有现货 |
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10MG | ¥2406 | 有现货 |
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25MG | ¥4236 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Cirsimaritin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Cirsimaritin 具有抗菌、抗炎、抗肿瘤、抗氧化和肾脏保护作用。 Cirsimaritin 与 GABAA 受体上的苯二氮卓位点结合较弱。
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产品描述Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.(In Vitro):Cirsimaritin inhibits the growth of tumor cells and induced mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt . Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner .(In Vivo):Cirsimaritin significantly reduces anxiety in mice. The high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg).
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体外实验——
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体内实验Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number6601-62-3
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分子量314.293
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分子式C17H14O6
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 22.73 mg/mL (72.32 mM)
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SMILESCOc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(O)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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