021-51111890
购物车（）
sales@molnova.cn
Cilostazol
CAS No. 73963-72-1
Cilostazol ( OPC 13013;OPC 21 )
产品货号. M15825 CAS No. 73963-72-1
Cilostazol (OPC 13013, OPC 21) is a potent inhibitor of PDE3A with IC50 of 0.2 uM; inhibits platelet aggregation and has considerable antithrombotic effects in vivo.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥316 | 有现货 |
|
| 50MG | ￥429 | 有现货 |
|
| 100MG | ￥624 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Cilostazol
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Cilostazol (OPC 13013, OPC 21) is a potent inhibitor of PDE3A with IC50 of 0.2 uM; inhibits platelet aggregation and has considerable antithrombotic effects in vivo.
-
产品描述Cilostazol (OPC 13013, OPC 21) is a potent inhibitor of PDE3A with IC50 of 0.2 uM; inhibits platelet aggregation and has considerable antithrombotic effects in vivo. The compound relaxes vascular smooth muscle and inhibits mitogenesis and migration of vascular smooth muscle cells; also upregulates autophagy via SIRT1 activation, has preventive effects on various central nervous system (CNS) diseases.Stroke Approved
-
同义词OPC 13013;OPC 21
-
通路Angiogenesis
-
靶点PDE
-
受体PDE3
-
研究领域Neurological Disease
-
适应症Stroke
化学信息
-
CAS Number73963-72-1
-
分子量369.46
-
分子式C20H27N5O2
-
纯度>98% (HPLC)
-
溶解度10 mM in DMSO
-
SMILESC1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4
-
化学全称2(1H)-Quinolinone, 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Schrr K, et al. Diabetes Obes Metab. 2002 Mar;4 Suppl 2:S14-9.
2. Lee HR, et al. PLoS One. 2015 Aug 5;10(8):e0134486.
3. Qi DS, et al. Brain Res. 2016 Dec 15;1653:67-74.
2. Lee HR, et al. PLoS One. 2015 Aug 5;10(8):e0134486.
3. Qi DS, et al. Brain Res. 2016 Dec 15;1653:67-74.
产品手册
关联产品
-
Tofimilast
Tofimilast (CP-325366) is a potent, selective PDE4 inhibitor with IC50 of 23, 13 and 13 nM for PDE4A, PDE4B, and PDE4D, respectively.
-
Rolipram
A potent, selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
-
Lotamilast
Lotamilast (RVT 501, E6005) is apotent, selective PDE4 inhibitor with IC50 of 2.8 nM, suppresses the production of various cytokines from human lymphocytes and monocytes with IC50 of 0.49-3.1 nM.
