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Chymase-IN-1
CAS No. 862090-74-2
Chymase-IN-1 ( —— )
产品货号. M26114 CAS No. 862090-74-2
Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥5249 | 有现货 |
|
| 10MG | ￥7468 | 有现货 |
|
| 25MG | ￥11178 | 有现货 |
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| 50MG | ￥15066 | 有现货 |
|
| 100MG | ￥20169 | 有现货 |
|
| 500MG | ￥39933 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Chymase-IN-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).
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产品描述Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).(In Vitro):Chymase-IN-1 (compound 5f) has a chymase Ki value of 36 nM and a Cat G Ki value of 9500 nM.(In Vivo):Chymase-IN-1 shows low oral bioavailability in rats (F=3%; oral t1/2=1.8 h).
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同义词——
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通路Others
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靶点Other Targets
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受体Akt; Angiotensin Receptor; PI3K; β-adrenoceptor
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研究领域——
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适应症——
化学信息
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CAS Number862090-74-2
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分子量431.8
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分子式C20H15ClNO4PS
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纯度>98% (HPLC)
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溶解度——
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SMILESOP(O)(=O)C(C(=O)Nc1ccc2ccccc2c1)c1csc2ccc(Cl)cc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Sun JJ, Kim HJ, Seo HG, et al. YS49,1-(alpha-naphtylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline,regulates angiotensin II-stimulated ROS production, JNK phosphorylation and vascular smooth muscle cell proliferation via the induction of heme oxygenase-1. Life Sci. 2008;82(11-12):600-7.
产品手册
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