Carubicin ( Carminomycin;Carminomycin I;Carminomicin I )

产品货号. M14357 CAS No. 39472-31-6

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Carubicin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Carubicin (Carminomycin) is an apoptosis inducer that targets the Golgi complex.
产品描述

Carubicin (Carminomycin) is an apoptosis inducer that targets the Golgi complex, induces apoptosis in CCRCC cells by a mechanism independent of p53 or HIF2, and induces cleavage of the Golgi protein p115 and the translocation of its C-terminal fragment to the nucleus.
同义词

Carminomycin;Carminomycin I;Carminomicin I
通路

Apoptosis
靶点

Apoptosis
受体

Apoptosis
研究领域

——
适应症

——

CAS Number

39472-31-6
分子量

513.50
分子式

C26H27NO10
纯度

>98% (HPLC)
溶解度

——
SMILES

O=C1C2=C(O)C([C@@H](O[C@@H]3O[C@@H](C)[C@@H](O)[C@@H](N)C3)C[C@](O)(C(C)=O)C4)=C4C(O)=C2C(C5=C1C(O)=CC=C5)=O
化学全称

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione

1. Woldemichael GM, et al. Cancer Res. 2011 Jan 1;71(1):134-42.
2. Tevyashova AN, et al. J Antibiot (Tokyo). 2004 Feb;57(2):143-50.

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