Carbobenzoxyproline

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Carbobenxyproline 是一种脯氨酸酶抑制剂。

Carbobenzoxyproline is a prolidase inhibitor.

Carbobenzoxyproline (6 mM; 0-10 d; pH=6.0) causes mitochondrial depolarization and increases cellular death by 33% as reported for long-term culture of fibroblasts from prolidase deficiency (PD) patients. Carbobenzoxyproline (0, 1, 3, 6 mM; 1 min; pH=6.0) results fibroblasts prolidase (FBP) hydrolysis, shows linear competitive inhibition.

Carbobenzoxyproline (60 mg/kg; injection; once daily; 3 weeks) serves as in vivo inhibitor of erythrocytes prolidase in mice model. Animal Model:C57Bl/6J mice (4-week-old)Dosage:60 mg/kg Administration:Injection; once daily for 3 weeks Result:Resulted significant reduction of erythrocytes prolidase activity.

Benzyloxycarbonylproline,Carbobenzoxy-S-proline

Others

Other Targets

prolidase

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——

1148-11-4

249.26

C13H15NO4

>98% (HPLC)

DMSO:Soluble

C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)O

——

(-20℃)

With Ice Pack

≥ 2 years