Koumine ( Koumine )

产品货号. M17971 CAS No. 1358-76-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Koumine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent.
产品描述

Koumine is an indole alkaloid. It reverses thermal hyperalgesia and mechanical allodynia induced by sciatic nerve chronic constriction injury (CCI) in rats in a dose-dependent manner. This effect is mediated by elevated allopregnanolone levels in the spinal cord.
同义词

Koumine
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

1358-76-5
分子量

306.4
分子式

C20H22N2O
纯度

98%
溶解度

DMSO : 31.25 mg/mL 101.99 mM;
SMILES

CN1CC2(C3CC4C5=NC6=CC=CC=C6C52CC1C3CO4)C=C
化学全称

(4aR,6R,11cS)-2-methyl-11c-vinyl-1,2,3,4,4a,5,6,11c-octahydro-6,4-(epoxymethano)-3,11b-methanopyrido[4,3-c]carbazole

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