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CAY10602
CAS No. 374922-43-7
CAY10602 ( CAY10602; CAY-10602; CAY 10602 )
产品货号. M18489 CAS No. 374922-43-7
CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥381 | 有现货 |
|
| 10MG | ￥462 | 有现货 |
|
| 25MG | ￥786 | 有现货 |
|
| 50MG | ￥1482 | 有现货 |
|
| 100MG | ￥2633 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CAY10602
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate.
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产品描述CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-dependently suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells, with approximately 75% inhibition achieved at 60 μM, without cytotoxicity.
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同义词CAY10602; CAY-10602; CAY 10602
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通路Others
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靶点Other Targets
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受体SIRT1
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研究领域——
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适应症——
化学信息
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CAS Number374922-43-7
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分子量418.44
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分子式C22H15FN4O2S
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纯度98%
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溶解度DMSO : 100 mg/mL 238.98 mM;
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SMILESFc1ccc(cc1)n1c2nc3ccccc3nc2c(c1N)S(=O)(=O)c1ccccc1
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化学全称1-(4-fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Hppner S, et al. Fragmentation studies of SIRT1-activating drugs and their detection in human plasma for doping control purposes. Rapid Commun Mass Spectrom. 2013 Jan 15;27(1):35-50.
产品手册
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