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CADD522

CAS No. 199735-88-1

CADD522 ( MFCD00167693 )

产品货号. M21954 CAS No. 199735-88-1

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activityCADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥348 有现货
10MG ¥494 有现货
25MG ¥1077 有现货
50MG ¥1831 有现货
100MG ¥3216 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    CADD522
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activityCADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.
  • 产品描述
    CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity.CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.
  • 同义词
    MFCD00167693
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    runt-related transcription factor-2 (RUNX2)-DNA
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    199735-88-1
  • 分子量
    326.17
  • 分子式
    C15H13Cl2NO3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:245 mg/ml(751.14 mM; Need ultrasonic)
  • SMILES
    OC(=O)C1C2CC(C=C2)C1C(=O)Nc1ccc(Cl)c(Cl)c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kim MS, et al. Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity. Oncotarget. 2017 Aug 10;8(41):70916-70940.
产品手册
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