021-51111890
购物车（）
sales@molnova.cn
CUR61414
CAS No. 334998-36-6
CUR61414 ( —— )
产品货号. M26658 CAS No. 334998-36-6
CUR61414 is an inhibitor of cell permeable Hedgehog signaling pathway (IC50: 100-200 nM) and selectively binds to smoothened (Smo) (Ki: 44 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥551 | 有现货 |
|
| 5MG | ￥915 | 有现货 |
|
| 10MG | ￥1531 | 有现货 |
|
| 25MG | ￥3054 | 有现货 |
|
| 50MG | ￥4690 | 有现货 |
|
| 100MG | ￥6707 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称CUR61414
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述CUR61414 is an inhibitor of cell permeable Hedgehog signaling pathway (IC50: 100-200 nM) and selectively binds to smoothened (Smo) (Ki: 44 nM).
-
产品描述CUR61414 is an inhibitor of cell permeable Hedgehog signaling pathway (IC50: 100-200 nM) and selectively binds to smoothened (Smo) (Ki: 44 nM). CUR-61414 can induce apoptosis in cancer cells without affecting neighboring non-tumor cells.(In Vitro):CUR61414 arrests the proliferation of basal cells within the BCC-like lesions and induces cell apoptosis and complete regression of the lesions, without affecting neighboring non-tumor cells.(In Vivo):CUR61414 regresses these lesions in the mice exposed to UV light irradiation and produces many microscopic BCC-like basaloid lesions throughout their skin.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number334998-36-6
-
分子量550.7
-
分子式C31H42N4O5
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCOc1cccc(CN([C@H]2C[C@H](N(Cc3ccc4OCOc4c3)C2)C(=O)N2CCNCC2)C(=O)CC(C)(C)C)c1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Uesawa M, Muroi K, Ozawa K. Plasmapheresis-refractory transplantation-associated thrombotic microangiopathy successfully treated with pravastatin and limaprost alfadex. Ther Apher Dial. 2013 Aug;17(4):462-3.
产品手册
关联产品
-
β-lonone
β-lonone is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetableswith?anti-proliferative anti-metastatic.
-
Tylosin
Tylosin (Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms.
-
2-Phenylethylamine h...
2-Phenylethylamine hydrochloride acts as neuromodulator in the central nervous system.?It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes.
