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C188-9（b）
CAS No. 432001-19-9
C188-9（b） ( C188-9; C 188-9; C-188-9 )
产品货号. M18547 CAS No. 432001-19-9
C188-9 is a Stat3 inhibitor with an IC50 of 4-7 μM.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥437 | 有现货 |
|
| 5MG | ￥721 | 有现货 |
|
| 10MG | ￥1013 | 有现货 |
|
| 25MG | ￥2130 | 有现货 |
|
| 50MG | ￥3386 | 有现货 |
|
| 100MG | ￥5063 | 有现货 |
|
| 500MG | ￥10773 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称C188-9（b）
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述C188-9 is a Stat3 inhibitor with an IC50 of 4-7 μM.
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产品描述C188-9 is a STAT3 inhibitor. HDM-induced airway inflammation, remodeling, and Th2/Th17-type cell accumulation involve STAT3 activation that can be prevented by C188-9 treatment. STAT3 inhibition with C188-9 resulted in attenuated skin fibrosis, myofibroblast accumulation, pro-fibrotic gene expression and collagen deposition in both mouse models of skin fibrosis. C188-9 decreased in vitro dermal fibroblast production of fibrotic genes induced by IL-6 trans-signalling and TGF-β. Finally, TGF-β induced phosphotyrosylation of STAT3 in a SMAD3-dependent manner.
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同义词C188-9; C 188-9; C-188-9
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通路Others
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靶点Other Targets
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受体STAT3
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研究领域Cancer
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适应症——
化学信息
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CAS Number432001-19-9
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分子量471.52
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分子式C27H21NO5S
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纯度98%
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溶解度DMSO : ≥ 62 mg/mL; 131.49 mM
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SMILESO=S(=O)(Nc4cc(c1c2ccccc2ccc1O)c(O)c3ccccc34)c5ccc(OC)cc5
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化学全称N-(1',2-dihydroxy-[1,2'-binaphthalen]-4'-yl)-4-methoxybenzenesulfonamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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