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Unifiram

CAS No. 272786-64-8

Unifiram ( —— )

产品货号. M28161 CAS No. 272786-64-8

Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥429 有现货
5MG ¥616 有现货
10MG ¥875 有现货
25MG ¥1563 有现货
50MG ¥2519 有现货
100MG ¥3977 有现货
500MG ¥8910 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Unifiram
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.
  • 产品描述
    Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.(In Vivo):Unifiram (0.1 mg kg?1 i.p.) was able to prevent amnesia induced by scopolamine (0.8 mg kg?1 i.p.) in the rat Morris watermaze test. In the rat social learning test, Unifiram (0.1 mg kg?1 i.p.) injected in adults rats reduced the duration of active exploration of the familiar partner in the second session of the test. Unifiram, similarly to piracetam, reduced the duration of hypnosis induced by pentobarbital. At the highest effective doses, the investigated compound did not impair motor coordination (rota rod test), nor modified spontaneous (Animex).
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    15-PGDH
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    272786-64-8
  • 分子量
    298.3
  • 分子式
    C13H15FN2O3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Fc1ccc(cc1)S(=O)(=O)N1CCN2C(CCC2=O)C1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Niesen FH, et al. High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. PLoS One. 2010 Nov 2;5(11):e13719.
产品手册
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