Unifiram
CAS No. 272786-64-8
Unifiram ( —— )
产品货号. M28161 CAS No. 272786-64-8
Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥429 | 有现货 |
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5MG | ¥616 | 有现货 |
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10MG | ¥875 | 有现货 |
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25MG | ¥1563 | 有现货 |
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50MG | ¥2519 | 有现货 |
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100MG | ¥3977 | 有现货 |
|
500MG | ¥8910 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Unifiram
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.
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产品描述Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.(In Vivo):Unifiram (0.1 mg kg?1 i.p.) was able to prevent amnesia induced by scopolamine (0.8 mg kg?1 i.p.) in the rat Morris watermaze test. In the rat social learning test, Unifiram (0.1 mg kg?1 i.p.) injected in adults rats reduced the duration of active exploration of the familiar partner in the second session of the test. Unifiram, similarly to piracetam, reduced the duration of hypnosis induced by pentobarbital. At the highest effective doses, the investigated compound did not impair motor coordination (rota rod test), nor modified spontaneous (Animex).
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同义词——
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通路Others
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靶点Other Targets
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受体15-PGDH
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研究领域——
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适应症——
化学信息
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CAS Number272786-64-8
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分子量298.3
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分子式C13H15FN2O3S
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纯度>98% (HPLC)
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溶解度——
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SMILESFc1ccc(cc1)S(=O)(=O)N1CCN2C(CCC2=O)C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Niesen FH, et al. High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. PLoS One. 2010 Nov 2;5(11):e13719.
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