
Butein
CAS No. 487-52-5
Butein ( AC1NQY7L | AC1N-QY7L | AC1N QY7L | CCG-208298 )
产品货号. M17521 CAS No. 487-52-5
Butein 是一种植物多酚,是从漆树中分离出来的。它可以抑制蛋白酪氨酸激酶、NF-κB和STAT3的激活,也可以抑制EGFR。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥413 | 有现货 |
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5MG | ¥648 | 有现货 |
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10MG | ¥875 | 有现货 |
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25MG | ¥1823 | 有现货 |
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50MG | ¥2940 | 有现货 |
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100MG | ¥4682 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Butein
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Butein 是一种植物多酚,是从漆树中分离出来的。它可以抑制蛋白酪氨酸激酶、NF-κB和STAT3的激活,也可以抑制EGFR。
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产品描述Butein is found in Rhuteic verniciflua and Butea monosperma. It induces cell cycle arrest and apoptosis in lung cancer cells, inhibits vessel spouting from aortic rings, and prevents hepatic stellate cell activation.
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体外实验Cell Viability Assay Cell Line:HeLa cells Concentration:10, 20, and 40 μM Incubation Time:24, 48, and 72 hours Result:Inhibited cell growth in a dose- and time-dependent manner.Western Blot Analysis Cell Line:HeLa cells Concentration:20 μM Incubation Time:24 hours Result:Decreased phosphorylation of AKT, ERK and p38 co-treatment with Cisplatin (20 μM).
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体内实验Animal Model:Nude mice (12 female 6- or 7-week old) with subcutaneous tumor xenografts Dosage:2 mg/kg Administration:Intraperitoneally; every 2 days; for 3 weeks Result:Enhanced the antitumor effects of Cisplatin in vivo.
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同义词AC1NQY7L | AC1N-QY7L | AC1N QY7L | CCG-208298
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通路Others
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靶点Other Targets
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受体EGFR
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研究领域Cancer
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适应症——
化学信息
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CAS Number487-52-5
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分子量272.25
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分子式C15H12O5
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 35 mg/mL128.56 mM
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SMILESc1cc(c(cc1/C=C/C(=O)c1c(cc(cc1)O)O)O)O
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化学全称(E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Yang EB, et al. Biochem Biophys Res Commun, 1998, 17, 245(2), 435-438.
产品手册




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