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SC-560

CAS No. 188817-13-2

SC-560 ( SC-560; SC 560; SC560 )

产品货号. M17399 CAS No. 188817-13-2

SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥267 有现货
5MG ¥421 有现货
10MG ¥753 有现货
25MG ¥1604 有现货
50MG ¥2041 有现货
100MG ¥2616 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    SC-560
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
  • 产品描述
    SC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.
  • 同义词
    SC-560; SC 560; SC560
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    COX-1; COX-2
  • 研究领域
    Cancer|Inflammation/Immunology
  • 适应症
    ——

化学信息

  • CAS Number
    188817-13-2
  • 分子量
    352.74
  • 分子式
    C17H12ClF3N2O
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL
  • SMILES
    COc1ccc(cc1)n1c(cc(n1)C(F)(F)F)c1ccc(cc1)Cl
  • 化学全称
    5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13313-8.
产品手册
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