Bromosporine ( Bromosporine )

产品货号. M18093 CAS No. 1619994-69-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Bromosporine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.
产品描述

Bromosporine is a broad spectrum inhibitor for bromodomains and as such will be very useful in elucidating further biological roles of reader domains as well as a tool for the validation of functional assays. Proteins that contain BRDs have been implicated in the development of a large variety of diseases, including various cancers, inflammatory diseases and neurological diseases and the therapeutic potential of bromodomain inhibition has been shown in several of these diseases, such as HIV, cancer and inflammation.
同义词

Bromosporine
通路

Others
靶点

Other Targets
受体

BRD
研究领域

Others-Field
适应症

——

CAS Number

1619994-69-2
分子量

404.45
分子式

C17H20N6O4S
纯度

98%
溶解度

DMSO : ≥ 51.7 mg/mL; 127.83 mM
SMILES

CCOC(=O)Nc1cc(nn2c(C)nnc12)c1cc(NS(=O)(=O)C)c(C)cc1
化学全称

ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate

1.15th HELLENIC SYMPOSIUM OF MEDICINAL CHEMISTRY.

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