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BOS-318
CAS No. 2387633-15-8
BOS-318 ( —— )
产品货号. M28989 CAS No. 2387633-15-8
BOS-318 is a Furin inhibitor with slowly dissociating, highly selective, and cell-pemeable characteristcs.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥786 | 有现货 |
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| 10MG | ￥1288 | 有现货 |
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| 25MG | ￥2608 | 有现货 |
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| 50MG | ￥4155 | 有现货 |
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| 100MG | ￥6051 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BOS-318
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述BOS-318 is a Furin inhibitor with slowly dissociating, highly selective, and cell-pemeable characteristcs.
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产品描述BOS-318 is a Furin inhibitor with slowly dissociating, highly selective, and cell-pemeable characteristcs.(In Vitro):BOS-318 (0.001-1 μM) provides cytoprotection against toxicity in CuFi-1 cells induced by P aeruginosa exotoxin A (PEA). BOS-318 (U2OS cells) to be approximately 13 times more potent against furin than PCSK5 (IC50 = 25.3 nM), 24 times more potent that PCSK7 (IC50 = 45.8 nM), and 110 times more potent than PCSK6 (IC50 = 209.4 nM). BOS-318 (0.3 μM, 2h or 48 h)reduces ENaC-mediated Na+ absorption in CF HBECs and protects aganist NE- and CF sputum-sol-mediated activation of ENaC.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number2387633-15-8
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分子量423.4
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分子式C17H31NO7P2
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纯度>98% (HPLC)
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溶解度——
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SMILESCCCCCCCCCCOc1ccc[n+](CC(P([O-])(O)=O)P(O)(O)=O)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Tsuburaya N, et al. A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model. Nat Commun. 2018 Jul 10;9(1):2668.
产品手册
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