Bivalirudin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Bivalirudin 是 α- 和 δ-凝血酶（Kis 分别为 2.56 和 1.84 nM）的可逆抑制剂，这两种酶表现出高纤维蛋白原凝血活性。

Bivalirudin is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM respectively) enzymes that exhibit high fibrinogen-clotting activities.(In Vivo):Bivalirudin (2 mg/kg) delays both the time for appearance of first thrombus and the time for occlusion in P2Y12+/+ arteries, although neither prevented vessel occlusion.

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Bivalirudin (2 mg/kg) delays both the time for appearance of first thrombus and the time for occlusion in P2Y12+/+?arteries, although neither prevented vessel occlusion.

Hirulog-1 | BG-8967

Autophagy

Thrombin

Thrombin

Cardiovascular Disease

heparin-induced thrombocytopenia

128270-60-0

2180.29

C98H138N24O33

>98% (HPLC)

In Vitro:?H2O : 10 mg/mL (4.59 mM)

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years