021-51111890
购物车（）
sales@molnova.cn
Batabulin
CAS No. 195533-53-0
Batabulin ( T138067 )
产品货号. M23886 CAS No. 195533-53-0
Batabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥988 | 有现货 |
|
| 10MG | ￥1442 | 有现货 |
|
| 25MG | ￥2535 | 有现货 |
|
| 50MG | ￥3750 | 有现货 |
|
| 100MG | ￥5411 | 有现货 |
|
| 500MG | ￥11178 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Batabulin
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Batabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization.
-
产品描述Batabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induce apoptotic cell death.
-
同义词T138067
-
通路Apoptosis
-
靶点Apoptosis
-
受体Apoptosis;Tubulin β
-
研究领域——
-
适应症——
化学信息
-
CAS Number195533-53-0
-
分子量371.3
-
分子式C13H7F6NO3S
-
纯度>98% (HPLC)
-
溶解度DMSO:100 mg/mL (269.35 mM; Need ultrasonic)
-
SMILESO=S(C1=C(F)C(F)=C(F)C(F)=C1F)(NC2=CC=C(OC)C(F)=C2)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Shan B, et al. Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5686-91.
产品手册
关联产品
-
physalin F
Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities.
-
Talampanel
Talampanel is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity.
-
CHM-1
CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits tubulin polymerization in vitro and in vivo.
