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BRD9-IN-28

CAS No. 1947372-67-9

BRD9-IN-28 ( —— )

产品货号. M13046 CAS No. 1947372-67-9

BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    BRD9-IN-28
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9.
  • 产品描述
    BRD9-IN-28 is a highly potent and selective BRD7/9 bromodomain inhibitor with pIC50 of 6.9, Kd of 68 nM for BRD9; slightly less potent against BRD7 (Kd=368 nM) and completely inactive against BAZ2B, little affinity across BRD proteins from sub-families 1-3 and 5-8, including BAZ2A and BAZ2B; shows weak affinity for the BRDs from CBP, p300 and FALZ.
  • 同义词
    ——
  • 通路
    Chromatin/Epigenetic
  • 靶点
    Bromodomain
  • 受体
    Bromodomain
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1947372-67-9
  • 分子量
    360.42
  • 分子式
    C21H20N4O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    1-(1-(imidazo[1,2-a]pyridin-5-yl)-7-morpholinoindolizin-3-yl)ethan-1-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Duncan. A. Hay, et al. Med. Chem. Commun., 2015, DOI: 10.1039/C5MD00152H.
产品手册
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