BRD-IN-26 ( —— )

产品货号. M13002 CAS No. 1915012-19-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

BRD-IN-26
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 with a KD of 124 nM.
产品描述

BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 with a KD of 124 nM, SMARCA2B and SMARCA4 with KD values of 262 and 417 nM, respectively; displays excellent selectivity over other bromodomains.
同义词

——
通路

Chromatin/Epigenetic
靶点

Bromodomain
受体

Bromodomain
研究领域

——
适应症

——

CAS Number

1915012-19-9
分子量

330.82
分子式

C17H19ClN4O
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

(E)-6-chloro-3-((4-methylpiperazin-1-yl)methylene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one

1. Sutherell CL, et al. J Med Chem. 2016 May 26;59(10):5095-101.

计算器

产品手册

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