BRD-IN-17 ( —— )

产品货号. M12999 CAS No. 1914047-59-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

BRD-IN-17
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3.
产品描述

BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3; attenuates adipocyte differentiation and dramatically decreases lipid accumulation; a first in class chemical probe for Family VIII bromodomains.
同义词

——
通路

Chromatin/Epigenetic
靶点

Bromodomain
受体

Bromodomain
研究领域

——
适应症

——

CAS Number

1914047-59-8
分子量

362.43
分子式

C21H22N4O2
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

(E)-3-((6S,9R)-4-(cyclopropylamino)-6,7,8,9-tetrahydro-5H-6,9-epiminocyclohepta[d]pyrimidin-10-yl)-1-(2-hydroxyphenyl)prop-2-en-1-one

1. Gerstenberger BS, et al. J Med Chem. 2016 May 26;59(10):4800-11.

计算器

产品手册

关联产品

CBP bromodomain inhi...

a potent, selective CBP bromodomain inhibitor with IC50 of 69 nM, displays exquisite selectivity over BRD4(1) (IC50=18 uM) and the broader bromodomain family.
CPI-268456

A bromodomain-containing protein inhibitor.
BRD-IN-26

BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 with a KD of 124 nM.