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BML-210

CAS No. 537034-17-6

BML-210 ( BML210;BML 210 )

产品货号. M14907 CAS No. 537034-17-6

A novel histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥275 有现货
5MG ¥429 有现货
10MG ¥624 有现货
25MG ¥1037 有现货
50MG ¥1677 有现货
100MG ¥2989 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    BML-210
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A novel histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM.
  • 产品描述
    A novel histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM; inhibits the growth of all cell lines and promotes apoptosis in the human leukemia cell lines (NB4, HL-60, THP-1, and K562); induces growth inhibition and apoptosis and downregulates HDAC1-5 and DAPC complex expression levels in cervical cancer cells.
  • 同义词
    BML210;BML 210
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    HDAC
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    537034-17-6
  • 分子量
    339.43
  • 分子式
    C20H25N3O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 30 mg/mL
  • SMILES
    O=C(NC1=CC=CC=C1N)CCCCCCC(NC2=CC=CC=C2)=O
  • 化学全称
    Octanediamide, N1-(2-aminophenyl)-N8-phenyl-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Savickiene J, et al. Eur J Pharmacol. 2006 Nov 7;549(1-3):9-18.
2. Wong JC, et al. J Am Chem Soc. 2003 May 14;125(19):5586-7.
3. Borutinskaite VV, et al. Mol Biol Rep. 2012 Dec;39(12):10179-86.
产品手册
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