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BJJF078
CAS No. 2531244-56-9
BJJF078 ( —— )
产品货号. M36035 CAS No. 2531244-56-9
BJJF078 是一种氨基哌啶衍生物。BJJF078 是一种有效的重组人和小鼠谷氨酰胺转氨酶 (TG2) 活性的抑制剂，IC50 值分别为 41 和 54 nM。BJJF078 也抑制密切相关的 TG1 酶，其IC50 为 0.16 μM。 BJJF078 可用于多发性硬化症 (MS) 研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥620 | 有现货 |
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| 5MG | ￥872 | 有现货 |
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| 10MG | ￥1235 | 有现货 |
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| 25MG | ￥2057 | 有现货 |
|
| 50MG | ￥3065 | 有现货 |
|
| 100MG | ￥4429 | 有现货 |
|
| 200MG | ￥6319 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BJJF078
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述BJJF078 是一种氨基哌啶衍生物。BJJF078 是一种有效的重组人和小鼠谷氨酰胺转氨酶 (TG2) 活性的抑制剂，IC50 值分别为 41 和 54 nM。BJJF078 也抑制密切相关的 TG1 酶，其IC50 为 0.16 μM。 BJJF078 可用于多发性硬化症 (MS) 研究。
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产品描述BJJF078 is an aminopiperidine derivative. BJJF078 is a potent inhibitor of recombinant human and mouse Transglutaminase enzyme (TG2) activity, IC50 values of 41 and 54 nM, respectively. BJJF078 also inhibits the close related enzyme TG1, with an IC50 of 0.16 μM. BJJF078 can be used for Multiple sclerosis (MS) research.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Glutaminase
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研究领域——
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适应症——
化学信息
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CAS Number2531244-56-9
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分子量523.6
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分子式C27H29N3O6S
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纯度>98% (HPLC)
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溶解度——
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SMILESS(=O)(=O)(C=1C2=C(C(NC(=O)C3=CC(OC)=C(OC)C=C3)=CC=C2)C=CC1)N4CCC(NC(C=C)=O)CC4
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Chrobok NL, et al. Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis. PLoS One. 2018 Apr 24;13(4):e0196433.?
产品手册
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