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BG-45
CAS No. 926259-99-6
BG-45 ( BG45 )
产品货号. M16637 CAS No. 926259-99-6
A potent and selective HDAC3 inhibitor with IC50 of 289 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥284 | 有现货 |
|
| 5MG | ￥462 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
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| 25MG | ￥1426 | 有现货 |
|
| 50MG | ￥2406 | 有现货 |
|
| 100MG | ￥3864 | 有现货 |
|
| 200MG | ￥4957 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BG-45
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent and selective HDAC3 inhibitor with IC50 of 289 nM.
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产品描述A potent and selective HDAC3 inhibitor with IC50 of 289 nM; shows selectivity over HDAC1 and HDAC2; downregulates phosphorylation (Tyr705 and Ser727) of STAT3 and triggers hyperacetylation of STAT3 in MM cells; significantly enhances bortezomib-induced cytotoxicity; exhibits significant tumor growth inhibition in vivo in a murine xenograft model of human MM.
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同义词BG45
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC1;HDAC2;HDAC3;HDAC6
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研究领域Cancer
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适应症——
化学信息
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CAS Number926259-99-6
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分子量214.22
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分子式C11H10N4O
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 48 mg/mL
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SMILESO=C(C1=NC=CN=C1)NC2=CC=CC=C2N
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化学全称2-Pyrazinecarboxamide, N-(2-aminophenyl)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Minami J, et al. Leukemia. 2014 Mar;28(3):680-9.
2. Harada T, et al. Leukemia. 2017 May 11. doi: 10.1038/leu.2017.144.
2. Harada T, et al. Leukemia. 2017 May 11. doi: 10.1038/leu.2017.144.
产品手册
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