Aumitin
CAS No. 946293-78-3
Aumitin ( Aumitin )
产品货号. M16783 CAS No. 946293-78-3
Aumitin is a novel potent autophagy inhibitor with IC50 of 124 and 244 nM against starvation- and rapamycin- induced autophagy respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2535 | 有现货 |
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10MG | ¥4026 | 有现货 |
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25MG | ¥6423 | 有现货 |
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50MG | ¥9153 | 有现货 |
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100MG | ¥12312 | 有现货 |
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500MG | ¥24057 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Aumitin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Aumitin is a novel potent autophagy inhibitor with IC50 of 124 and 244 nM against starvation- and rapamycin- induced autophagy respectively.
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产品描述Aumitin is a novel potent autophagy inhibitor with IC50 of 124 and 244 nM against starvation- and rapamycin- induced autophagy respectively, targets mitochondrial complex I; inhibits LC3 lipidation, and p62 degradation by starvation- as well as rapamycin-induced autophagy dose-dependently in MCF7-LC3 cells, suggesting inhibition of autophagic flux; inhibits mitochondrial respiration by targeting complex I with IC50 of 0.11 uM in HeLa cells; Aumitin is a new tool compound for interrogating autophagy and mitochondrial respiration by means of complex I inhibition.
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同义词Aumitin
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通路Autophagy
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靶点Autophagy
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受体Autophagy
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研究领域——
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适应症——
化学信息
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CAS Number946293-78-3
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分子量429.91
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分子式C24H20ClN5O
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(NC1=CC=C(NC2=NC(NC3=CC=CC=C3)=CC(C)=N2)C=C1)C4=CC=CC=C4Cl
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化学全称2-chloro-N-(4-((4-methyl-6-(phenylamino)pyrimidin-2-yl)amino)phenyl)benzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Robke L, et al. Chem Sci. 2018 Feb 26;9(11):3014-3022.
产品手册
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